INNOVATIVE MEDICAL INTERVENTIONS FOR PREGNANCY

Abstract

Genetic disorders that can complicate pregnancy pose significant challenges to maternal and fetal health, necessitating innovative medical interventions. Gene therapy has emerged as a promising approach to address these disorders at their genetic root, offering personalized and targeted treatments. This comprehensive review synthesizes recent advancements in gene therapy techniques, including in utero interventions, prenatal genetic testing, and targeted gene delivery systems. Key topics explored include the role of gene therapy in managing congenital adrenal hyperplasia (CAH), spinal muscular atrophy (SMA), alpha-thalassemia, cystic fibrosis (CF), preeclampsia, and gestational diabetes. Ethical considerations, regulatory frameworks, and future directions in gene therapy research are also discussed. This review aims to provide insights into the transformative potential of gene therapy for improving outcomes in maternal-fetal health and addressing genetic disorders that complicate pregnancy.