EVALUTATING THE EFFICACY OF PROBIOTIC-ENRICHED NUTRITIONAL SUPPELEMENTS ON GUT HEALTH AND WEIGHT MANAGEMENT IN OBESE ADULT: A RANDOMIZED CONTROLLED TRIAL

Abstract

Background: Obesity is a serious worldwide health issue, directly associated with changes in gut microbiota and higher rates of metabolic disorders. Objective: The aim of this research was to assess the effectiveness of probioticsupplemented nutritional supplements in enhancing gut health and weight management among obese adults. Methodology: A randomized controlled trial for 12 weeks was carried out among 100 obese adults, aged 25–55 years, who were randomized to be given either a probiotic or a placebo supplement, with measurements of gut microbiota, anthropometric parameters, and metabolic indices before and after intervention. Results: Members of the probiotic group experienced marked reductions in body weight, BMI, and fat mass, with better blood glucose and lipid profiles; analysis of gut contents demonstrated higher levels of Lactobacillus and Bifidobacterium species. Conclusion: Probiotic supplementation could be an effective and safe addition to standard obesity management by promoting gut microbiota and metabolic health.