A REVIEW ON THE POSSIBLE EXPLANATIONS OF USING CASHEW (ANACARDIUM OCCIDENTALE LINN) NUT OIL TO FORM SEDDS

Abstract

Nigeria is a country with rich varieties of nuts such as Anacardium occidentale (cashew nut). It is important to optimize the available local raw materials in our environment for the benefits of rising pharmaceutical companies in the country. To reduce inconveniences, it is better to reduce pharmaceutical formulations through the use of local oils (of excipient and surfactant properties). A work on cashew kernel oil extraction and it's physicochemical properties is beneficial, therewith, it can be utilized for making self-emulsifying properties such as self-emulsifying drug delivery system (SEDDS). SEDDS has oil and surfactant -based ability characterized with the potential of slow agitation that emulsified speedily in water. Certainly, cashew nut is an available and cheap nut in various parts of Nigeria, such as northern region, middle belt, and southern parts. The nut is rich in oleic acid, therewith, easily exploited for pharmaceutical applications and benefits. The self-emulsifying property in lowered interfacial tension (between the oil, and water interface), aided by surfactants (and cosurfactants) will give rise to boosted solubility (by minimized precipitation). The local nature of cashew invariably provides enough amount of oleic acid that aid formulations, advantageously to the pharmaceutical industries. The application locally-based products like cashew in pharmaceutical fields could not be overstated. One of the  applications of cashew is formation of SEDDS. We cannot be able to form the SEDDS unless if we have details broaching about SEDDS. Therefore, this paper performs a review of SEDDS under certain headings. This paper makes a sufficient description of the items below: emulsions, self-emulsifying drug delivery systems (SEDDS), factors affecting SEDDS, method of preparing SEDDS, formulations SEDDS, components of SEDDS, characterization of SEDDS, stability of SEDDS, future, imitation, and the likes.