IMPACT OF 1.5% MONOSODIUM GLUTAMATE SOLUTION ON LIPID BIOMARKERS OF ALBINO RATS (RATTUS NOVERGICUS)

Abstract

Monosodium glutamate (MSG) is a common food additive used to enhance flavor in processed foods. Despite being classified as generally safe by regulatory agencies, its potential health effects have been a subject of ongoing research. The trial was done to investigate the effect of MSG on cholesterol level, Triglyceride (TG) level, low density lipoprotein (LDL), and High-density lipoprotein (HDL) level of albino rats. The findings of the current study demonstrate that the effect of MSG on lipid profile (including Free Cholesterol, triglyceride, LDL, and HDL-C) leads to a significant increase in mild doses compared to the control group. It was observed that there was a notable increase in cholesterol levels, triglycerides, and low-density lipoprotein (LDL), accompanied by a decrease in high-density lipoprotein (HDL). The average triglyceride values in the control group of male rats were 122.7320, whereas in the MSG group, it was 122.0340, resulting in a difference of 0.69800. Similarly, the average cholesterol values in the control group were 153.9920, whereas in the MSG group, it was 110.9880, resulting in a group.