BIOFUNCTIONAL EFFECTS OF BUTTON MUSHROOM (AGARICUS BISPORUS) POWDER IN THE MANAGEMENT OF LIPID PEROXIDATION BIOMARKERS IN ANIMAL MODEL

Abstract

Hypercholesterolemia is a primary cause of atherosclerosis and is a contributing factor to other risk factors. Low plasma cholesterol concentrations in the community typically lead to a lower incidence of coronary heart disease. Button mushroom is a highly nutritious food item, contain -full of vitamins and fiber as well as several type of phytonutrients. Therapeutically, button mushrooms enhance immunological health, exhibit antioxidant qualities, aid in cancer prevention, promote heart health, help with weight loss, and improve gut health through prebiotic fibers. The purpose of current research to investigate the button mushroom against the dyslipidemia in rat model. For this purpose firstly button mushroom were analyzed for it chemical composition after that to check its evaluation  in hyperlipidemia experimental rats were divided into 3 different groups including a control group (normal diet; n=10), Experimental group I (hyperlipidemia rats treated with Button mushroom powder(200 mg/kg, n=10), Experimental group II (hyperlipidemia rats treated with Button mushroom powder (400 mg/kg, n=10). The results showed that Button mushroom contained moisture (12.5±0.33%), nitrogen free extract (52.2±2.7%) ash (7.92±0.23%), crude fiber (12.65±3%), crude protein (17.21±2%) and crude fat (1.86±1%). Along with appreciable content of contains magnesium (1001±4.3), Manganese (15.1±0.05), zinc (52.4±0.3), Sodium (64.65±0.02), Potassium (15.77±2.1), Iron (34.34±0.22) and copper (8.5±0.02). It’s also showed that both treatment  groups showed a decrease in plasma lipid parameters and increased high- density lipoprotein content in blood as compared to control group. So, it was concluded that button mushroom depicts a significant impact on the treatment of hyperlipidemia and associated parameters.